matt mingay

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I currently work as a Data Scientist (Bioinformatics) at the Joint Genome Institute at Lawrence Berkeley National Laboratory where I develop analysis pipelines and tools for epigenomic experiments (chIP-seq, methyl-seq, RNA-seq).

Vitamin C induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia Nature Leukemia

Figure 2

Figure 2. Vitamin C induces methylome remodelling in IDH1 R132H expressing cells

Figure 3

Figure 3. Vitamin C treatment leads to demethylation at enhancers that become active in the myeloid lineage specifically


Epigenetic and transcriptional determinants of the human breast Nature Communications

Breast Figure 1

Figure 2. Intron retention and mammary cell type-specific miRNAs and long noncoding RNAs.

Figure 3

Figure 3. Regulatory asymmetry between myoepithelial and luminal cell types.


Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98–HOXA9 induced myeloid disease Nature Leukemia

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Figure 3. Microarray analysis identifies overexpression of DNMT1.

zebrafish figure

Figure 4. DAC and Indo function synergistically with VPA to restore hematopoiesis in NHA9 transgenic zebrafish